William Munny is a retired, once-ruthless killer turned gentle widower and hog farmer. To help support his two motherless children, he accepts one last bounty-hunter mission to find the men who brutalized a prostitute. Joined by his former partner and a cocky greenhorn, he takes on a corrupt sheriff.
A botched robbery indicates a police informant, and the pressure mounts in the aftermath at a warehouse. Crime begets violence as the survivors -- veteran Mr. White, newcomer Mr. Orange, psychopathic parolee Mr. Blonde, bickering weasel Mr. Pink and Nice Guy Eddie -- unravel.